Values in global variables

 
A query, when I have an Expert Advisor  running, and change the timeframe in platform Metatrader4, the EA restarts, and rerun the INIT function, my question is will also reset the values ​​of global variables?
 

I assume you mean globally declared variables, not Global variables

Global variables can be initialized only once after program loading into client terminal memory.

Rerunning init is not reloading, so NO

And next time, use the search function as your question has been asked many times.